Asthana A, Ramanan P, Hirschi A, Guiley KZ, Wijeratne TU, Shelansky R, Doody MJ, Narasimhan H, Boeger H, Tripathi S, Müller GA, Rubin SM.Nat Commun. 2022 Jan 26;13(1):526. doi: 10.1038/s41467-022-28094-1.
Wijeratne TU, Guiley KZ, Lee HW, Müller GA, Rubin SM.J Biol Chem. 2022 Sep;298(9):102319. doi: 10.1016/j.jbc.2022.102319. Epub 2022 Aug 1.
Putta S, Alvarez L, Lüdtke S, Sehr P, Müller GA, Fernandez SM, Tripathi S, Lewis J, Gibson TJ, Chemes LB, Rubin SM.
Tambo CS, Tripathi S, Perera BGK, Maly DJ, Bridges AJ, Kiss G, Rubin SM.ACS Chem Biol. 2023 Feb 17;18(2):431-440. doi: 10.1021/acschembio.3c00015. Epub 2023 Feb 1.PMID: 36724382Free PMC article.
HDAC activity is dispensable for repression of cell-cycle genes by DREAM and E2F:RB complexes.
Barrett AK, Shingare MR, Rechtsteiner A, Rodriguez KM, Le QN, Wijeratne TU, Mitchell CE, Membreno MW, Rubin SM, Müller GA.Nat Commun. 2024 May 24;15(1):4450. doi: 10.1038/s41467-024-48724-0.
Structural mechanism for the recognition of E2F1 by the ubiquitin ligase adaptor Cyclin F.
Ngoi P, Wang X, Putta S, Da Luz RF, Serrão VHB, Emanuele MJ, Rubin SM. Proc Natl Acad Sci U S A. 2025 Jul;122(26):e2501057122. doi: 10.1073/pnas.2501057122. Epub 2025 Jun 23.PMID: 40549918
An order-to-disorder structural switch activates the FoxM1 transcription factor.
Marceau AH, Brison CM, Nerli S, Arsenault HE, McShan AC, Chen E, Lee HW, Benanti JA, Sgourakis NG, Rubin SM.
Elife. 2019 May 28;8. pii: e46131. doi: 10.7554/eLife.46131.
p27 allosterically activates cyclin-dependent kinase 4 and antagonizes palbociclib inhibition
Guiley KZ, Stevenson JW, Lou K, Barkovich KJ, Kumarasamy V, Wijeratne TU, Bunch KL, Tripathi S, Knudsen ES, Witkiewicz AK, Shokat KM, Rubin SM.
Science. 2019 Dec 13;366(6471). pii: eaaw2106. doi: 10.1126/science.aaw2106.
Structural mechanism of Myb–MuvB assembly
Guiley KZ, Iness AN, Saini S, Tripathi S, Lipsick JS, Litovchick L, Rubin SM. Proc Natl Acad Sci U S A. 2018 Oct 2;115(40):10016-10021.
Structural basis of divergent cyclin-dependent kinase activation by Spy1/RINGO proteins.
McGrath DA, Fifield BA, Marceau AH, Tripathi S, Porter LA, Rubin SM. EMBO J. 2017 Aug 1;36(15):2251-2262.
Conservation and divergence of C-terminal domain structure in the retinoblastoma protein family.
Liban TJ, Medina EM, Tripathi S, Sengupta S, Henry RW, Buchler NE, Rubin SM. Proc Natl Acad Sci U S A. 2017 May 9;114(19):4942-4947.
Structural basis for LIN54 recognition of CHR elements in cell cycle-regulated promoters.
Marceau AH, Felthousen JG, Goetsch PD, Iness AN, Lee HW, Tripathi SM, Strome S, Litovchick L, Rubin SM. Nat Commun. 2016 Jul 28;7:12301.
A Strategy for Direct Chemical Activation of the Retinoblastoma Protein.
Pye CR, Bray WM, Brown ER, Burke JR, Lokey RS, Rubin SM. ACS Chem Biol. 2016 May 20;11(5):1192-7.
Structural mechanisms of DREAM complex assembly and regulation.
Guiley KZ, Liban TJ, Felthousen JG, Ramanan P, Litovchick L, Rubin SM. Genes Dev. 2015 May 1;29(9):961-74. doi: 10.1101/gad.257568.114. Epub 2015 Apr 27.
Molecular mechanisms underlying RB protein function.
Dick FA, Rubin SM. Nat Rev Mol Cell Biol. 2013 May;14(5):297-306.
Deciphering the retinoblastoma protein phosphorylation code.
Rubin SM. Trends Biochem Sci. 2013 Jan;38(1):12-9.
Structures of inactive retinoblastoma protein reveal multiple mechanisms for cell cycle control.
Burke JR, Hura GL, Rubin SM. Genes Dev. 2012 Jun 1;26(11):1156-66.
